The Influence of Pubertal Development on Autoantibody Appearance and Progression to Type 1 Diabetes in the TEDDY Study.

Katharina WarnckeRoy TamuraDesmond A SchatzRiitta VeijolaAndrea K SteckBeena AkolkarWilliam HagopianJeffrey P KrischerÅke LernmarkMarian J RewersJorma ToppariRichard McIndoeAnette-G ZieglerKendra VehikMichael J HallerHelena Elding Larsson

Published in: Journal of the Endocrine Society (2024)

Rapid weight gain during puberty is associated with development of islet autoimmunity. Puberty itself had no significant influence on the appearance of autoantibodies or type 1 diabetes. Further studies are needed to better understand the underlying mechanisms.

Keyphrases

type diabetes
weight gain
body mass index
birth weight
glycemic control
cardiovascular disease
insulin resistance
metabolic syndrome
skeletal muscle
celiac disease
quantum dots
preterm birth