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Investigating the role of inflammation in keratoconus: A retrospective analysis of 551 eyes.

Prem A H NichaniBenjamin SolomonTanya TrinhMichael MimouniDavid RootmanNeera SingalClara C Chan
Published in: European journal of ophthalmology (2022)
MMP9 positive keratoconic eyes had significantly higher Kmax readings which may correlate with increased disease severity, supporting an association between keratoconus and inflammation. Further research is warranted to evaluate the role of targeted therapy and contact lens use on MMP9 levels in keratoconic eyes and whether disease progression is affected.
Keyphrases
  • optical coherence tomography
  • cataract surgery
  • oxidative stress
  • cell migration