Prostate adenocarcinoma with mucinous features - is it PSMA avid?
Patrick J HorsleyGemma Sheehan-DareKaterina MastrocostasCaroline FungAndrew B KneeboneThomas N EadeLouise EmmetAndre LalakGeorge HrubyPublished in: Journal of medical imaging and radiation oncology (2021)
Mucinous prostate adenocarcinoma represents <0.1% of prostate cancers. To our knowledge, no previous report has described the 68 Ga-PSMA-PET characteristics of this entity at the primary site. We present a case of a fit 85-year-old with PSA 0.55 ng/mL and ISUP grade 4 acinar adenocarcinoma with mucinous features on biopsy. 68 Ga-PSMA-PET revealed an intensely avid primary lesion in the right prostate (SUVmax 10.9), concordant with biopsy findings and encompassing both the PI-RADS 5 lesion identified on MRI and a PI-RADS 1 lesion that presumably represented the mucinous component. The patient was treated with definitive radiotherapy to the prostate and lymph nodes with 6 months of androgen deprivation therapy.
Keyphrases
- pet ct
- prostate cancer
- benign prostatic hyperplasia
- low grade
- locally advanced
- pet imaging
- squamous cell carcinoma
- positron emission tomography
- radical prostatectomy
- lymph node
- healthcare
- early stage
- magnetic resonance imaging
- computed tomography
- radiation therapy
- rectal cancer
- ultrasound guided
- stem cells
- magnetic resonance
- replacement therapy
- sentinel lymph node
- newly diagnosed