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Extracellular vesicle-associated miR-135b and -135a regulate stemness in Group 4 medulloblastoma cells by targeting angiomotin-like 2.

Seung Ah ChoiEun Jung KohRyong Nam KimJung Woo ByunJi Hoon PhiJeyul YangKyu-Chang WangAe Kyung ParkDo Won HwangJi Yeoun LeeSeung Ki Kim
Published in: Cancer cell international (2020)
Our results indicated that inhibition of miR-135b or miR-135a leads to suppress stemness of BTSC through modulation of AMOTL2.
Keyphrases
  • stem cells
  • epithelial mesenchymal transition
  • cell proliferation
  • long non coding rna
  • cancer stem cells
  • long noncoding rna
  • signaling pathway