Disseminated tumor cells are not associated with established risk factors, L1CAM immunoreactivity and outcome in endometrial carcinoma.
Stefan KommossAndreas D HartkopfBernhard KrämerAnne-Kathrin BunzFriederike GrevenkampFelix KommossJana PasternakSabine M ArbabiMarkus WallwienerAnnette StaeblerSigurd F LaxSara Y BruckerFlorin-Andrei TaranPublished in: Journal of cancer research and clinical oncology (2017)
We were able to confirm previous findings of DTC presence in a large well-characterized cohort of endometrial carcinoma patients. DTC are detectable in almost one-fifth of endometrial carcinoma and occur less frequently with a MELF pattern of invasion. Further studies investigating the role of DTC in endometrial carcinoma are warranted.