Electrochemical Nanobiosensors for Detection of Breast Cancer Biomarkers.
Veronika GajdosovaLenka LorencovaPeter KasakJan TkacPublished in: Sensors (Basel, Switzerland) (2020)
This comprehensive review paper describes recent advances made in the field of electrochemical nanobiosensors for the detection of breast cancer (BC) biomarkers such as specific genes, microRNA, proteins, circulating tumor cells, BC cell lines, and exosomes or exosome-derived biomarkers. Besides the description of key functional characteristics of electrochemical nanobiosensors, the reader can find basic statistic information about BC incidence and mortality, breast pathology, and current clinically used BC biomarkers. The final part of the review is focused on challenges that need to be addressed in order to apply electrochemical nanobiosensors in a clinical practice.
Keyphrases
- label free
- gold nanoparticles
- circulating tumor cells
- ionic liquid
- molecularly imprinted
- clinical practice
- risk factors
- mesenchymal stem cells
- healthcare
- cardiovascular events
- gene expression
- genome wide
- loop mediated isothermal amplification
- coronary artery disease
- bone marrow
- transcription factor
- quantum dots
- mass spectrometry