The neurotrophic activities of brain-derived neurotrophic factor are potentiated by binding with apigenin, a common flavone in vegetables, in stimulating the receptor signaling.
Alex Xiong GaoTracy Chen-Xi XiaLish Sheng-Ying LinTina Ting-Xia DongKarl Wah-Keung TsimPublished in: CNS neuroscience & therapeutics (2023)
Apigenin potentiates the neurotrophic activities of BDNF through direct binding, which may serve as a possible treatment for its curative efficiency in neurodegenerative diseases and depression.