Differential Recognition of Mycobacterium tuberculosis-Specific Epitopes as a Function of Tuberculosis Disease History.

Thomas J ScribaChelsea CarpenterSebastian Carrasco ProJohn SidneyMunyaradzi MusvosviVirginie RozotGrégory SeumoisSandy L RosalesPandurangan VijayanandDelia GolettiEdward MakgotlhoWillem HanekomMark HatherillBjoern PetersAlessandro SetteCecilia S Lindestam Arlehamn

Published in: American journal of respiratory and critical care medicine (2017)

Preferential loss of T-cell reactivity to Mtb epitopes that are homologous to bacteria in the microbiome in persons with previous TB disease may reflect long-term effects of antibiotic TB treatment on the microbiome.

Keyphrases

mycobacterium tuberculosis
pulmonary tuberculosis
emergency department
combination therapy
hiv aids