Immediate drop of urine osmolality upon tolvaptan initiation predicts impact on renal prognosis in patients with ADPKD.
Taro AkihisaHiroshi KataokaShiho MakabeShun ManabeRie YoshidaYusuke UshioMasayo SatoAiji YajimaNorio HanafusaKen TsuchiyaKosaku NittaJunichi HoshinoToshio MochizukiPublished in: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association (2023)
U-Osm can be measured easily and rapidly, and U-Osm change within a short time after tolvaptan initiation may be a useful index for the renal prognosis in actual clinical practice.