Acute Bacterial Skin and Skin-Structure Infections, efficacy of Dalbavancin: a systematic review and meta-analysis.
Nuria Monteagudo-MartínezJulian Solis García Del PozoEduardo NavaIchiro IkutaMaría F GalindoJoaquin JordánPublished in: Expert review of anti-infective therapy (2020)
Either single dose or two dose dalbavancin treatment is as clinically effective as other antibiotics such as vancomycin and linezolid for the treatment of ABSSSIs.Abbreviations ABSSI: acute bacterial skin and skin-structure infection; AUC: area under the concentration-time curve; CE: clinical evaluable; CI: confidence interval; EOT: end of treatment; ITT: intention-to-treat; LOS: length of stay; MIC: minimum inhibitory concentration; MIC90: minimum concentration to inhibit growth of 90% of isolates; MR: methicillin resistant; MRSA: methicillin-resistant Staphylococcus aureus; MS: methicillin susceptible; MSSA: methicillin-susceptible Staphylococcus aureus; OPAT: Outpatient Parenteral Antimicrobial Therapy; OR: odds ratio; PI: penicillin intermediate; PR: penicillin resistant; PS penicillin susceptible; SIRS: systemic inflammatory response syndrome; SSTI: skin and soft tissue infection; TOC: test of cure; VR: vancomycin resistant; VS: vancomycin susceptible.
Keyphrases
- methicillin resistant staphylococcus aureus
- staphylococcus aureus
- soft tissue
- inflammatory response
- biofilm formation
- liver failure
- multiple sclerosis
- stem cells
- bone marrow
- mass spectrometry
- mesenchymal stem cells
- combination therapy
- computed tomography
- hepatitis b virus
- drug induced
- quantum dots
- ms ms
- aortic dissection
- toll like receptor
- acute respiratory distress syndrome
- lipopolysaccharide induced
- contrast enhanced
- pseudomonas aeruginosa
- lps induced