Homozygous familial hypercholesterolemia with stenosis of the left anterior descending coronary artery successfully treated with weekly low-density lipoprotein apheresis for 16 years without percutaneous coronary intervention.
Takanori YasuMasahiro ShimoyamaHiroshi WadaTomohiro IwakuraShigeru ToyodaAtsuhiko KawabeTakushi SugiyamaPublished in: Clinical case reports (2019)
We successfully treated a patient with homozygous familial hypercholesterolemia (HoFH) with stable coronary arterial disease using optimal medical therapy and low-density lipoprotein (LDL) apheresis for 16 years without percutaneous coronary intervention or bypass surgery. Intensive LDL lowering using apheresis and medication protected the patient from coronary atherosclerotic progression even in HoFH.
Keyphrases
- low density lipoprotein
- coronary artery
- percutaneous coronary intervention
- coronary artery disease
- coronary artery bypass
- st segment elevation myocardial infarction
- acute myocardial infarction
- acute coronary syndrome
- pulmonary artery
- st elevation myocardial infarction
- antiplatelet therapy
- coronary artery bypass grafting
- case report
- healthcare
- minimally invasive
- atrial fibrillation
- heart failure
- aortic stenosis
- stem cells
- aortic valve
- left ventricular
- bone marrow