Circulatory microRNA 23a and microRNA 23b and polycystic ovary syndrome (PCOS): the effects of body mass index and sex hormones in an Eastern Han Chinese population.

Weixi XiongYing LinLili XuAmin TamadonShien ZouFubo TianRuijin ShaoXin LiYi Feng

Published in: Journal of ovarian research (2017)

Both reduced levels and discordance between the expressions of miR-23a/b were observed in the women with PCOS and miR-23a/b were affected from testosterone and BMI, reversely. Therefore, miR-23a alteration in contrast with miR-23b is a better indicator for evaluation of PCOS than the miR-23b.

Keyphrases

polycystic ovary syndrome
cell proliferation
long non coding rna
insulin resistance
long noncoding rna
magnetic resonance
body mass index
south africa
metabolic syndrome
type diabetes
magnetic resonance imaging
adipose tissue
computed tomography