Relevance of comorbidities on initial combination therapy in pulmonary arterial hypertension.
Roberto BadagliaccaMichele D'AltoStefano GhioPaola ArgientoNatale Daniele BrunettiGavino CasuNadia CedroneMarco ConfalonieriMarco CordaMichele CorrealeCarlo D'AgostinoLucrezia De MicheleSerena Di MarinoDomenico FilomenaGiuseppe GalganoAlessandra GrecoCarlo LombardiGiovanna ManziValentina MercurioMassimiliano MulèGiuseppe PacioccoSilvia PapaEmanuele RomeoLaura ScelsiDavide StolfoPatrizio VituloCarmine Dario VizzaPublished in: ERJ open research (2022)
Initial oral combination therapy seems associated with a less effective response for patients with cardiovascular comorbidities compared with the others, related to the magnitude of treatment-induced decrease in PVR.