Cholangiocyte-derived exosomal long noncoding RNA H19 promotes cholestatic liver injury in mouse and humans.

Xiaojiaoyang LiRunping LiuZhiming HuangEmily C GurleyXuan WangJuan WangHongliang HeHu YangGuanhua LaiLuyong ZhangJasmohan Singh BajajMelanie WhiteWilliam M PandakPhillip B HylemonHuiping Zhou

Published in: Hepatology (Baltimore, Md.) (2018)

Cholangiocyte-derived exosomal-H19 plays a critical role in cholestatic liver injury. Serum exosomal H19 represents a noninvasive biomarker and potential therapeutic target for cholestatic diseases. (Hepatology 2018).

Keyphrases

liver injury
drug induced
long noncoding rna
risk assessment
human health