Tacrolimus Variability and Clinical Outcomes in the Early Post-lung Transplantation Period: Oral Versus Continuous Intravenous Administration.
Julia E M van DommelenHeleen GrootjansEsther V UijtendaalDieuwertje RuigrokBart LuijkMatthijs van LuinWouter BultDylan W de LangeNuray KusadasiJoep M DrooghAntoine C G EgbertsErik Alfons Maria VerschuurenMaaike A SikmaPublished in: Clinical pharmacokinetics (2024)
Administering tacrolimus orally directly after LuTx leads to a higher variability in blood concentrations compared to intravenous administration. There was no difference in the occurrence of AKI or transplant rejection.