Login / Signup

Tacrolimus Variability and Clinical Outcomes in the Early Post-lung Transplantation Period: Oral Versus Continuous Intravenous Administration.

Julia E M van DommelenHeleen GrootjansEsther V UijtendaalDieuwertje RuigrokBart LuijkMatthijs van LuinWouter BultDylan W de LangeNuray KusadasiJoep M DrooghAntoine C G EgbertsErik Alfons Maria VerschuurenMaaike A Sikma
Published in: Clinical pharmacokinetics (2024)
Administering tacrolimus orally directly after LuTx leads to a higher variability in blood concentrations compared to intravenous administration. There was no difference in the occurrence of AKI or transplant rejection.
Keyphrases
  • high dose
  • acute kidney injury
  • risk assessment
  • extracorporeal membrane oxygenation
  • low dose