Development and biological assessment of MMAE-trastuzumab antibody-drug conjugates (ADCs).

Sajad YaghoubiTohid GharibiMohammad Hossein KarimiMuhammad Sadeqi NezhadAlexander SeifalianReza TavakkolNader BagheriAsiyeh DezhkamMeghdad Abdollahpour-Alitappeh

Published in: Breast cancer (Tokyo, Japan) (2020)

MMAE-trastuzumab ADCs represent a promising therapeutic strategy to treat HER2-positive breast cancer.

Keyphrases

positive breast cancer
epidermal growth factor receptor
metastatic breast cancer
tyrosine kinase
cancer therapy