Asymmetric Wacker-Type Oxyallenylation and Azaallenylation of Cyclic Alkenes.
Shenghan TengZhiwei JiaoYonggui Robin ChiJianrong Steve ZhouPublished in: Angewandte Chemie (International ed. in English) (2019)
Palladium-catalyzed three-component carboetherification of cyclic alkenes proceeded to give trans adducts exclusively with excellent enantioselectivity through a Wacker-type pathway. The reaction is also applicable to other oxygen nucleophiles, such as water, phenols, and carboxylic acids, as well as some electron-poor aryl amines.
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