Minimum lesion detectability as a measure of PET system performance.
Stephen S AdlerJurgen SeidelPeter ChoykeMichael V KnoppKatherine BinzelJun ZhangCraig BarkerShielah ConantRoberto Maass-MorenoPublished in: EJNMMI physics (2017)
Besides demonstrating that the current state of the art clinical PET/CT systems have the same lesion detection ability, the study demonstrates how sensitive scan time can be to detecting small lesions which have a relatively small contrast uptake in the range of just 2:1. This should help guide imaging protocols to use longer scan times over regions of the subject in which small lesions are suspect.