The German version of the neurofibromatosis 2 impact on quality of life questionnaire correlates with severity of depression and physician-reported disease severity.

Anna Cecilia Lawson McLeanAnna FreierAaron Lawson McLeanJohannes KruseSteffen Rosahl

Published in: Orphanet journal of rare diseases (2023)

The NFTI-QOL-D is a reliable and useful tool to assess patient-reported QOL in German-speaking patients with NF2. The correlation of QOL with both psychological and physical disease parameters underlines the importance of individualized interdisciplinary patient care for NF2 patients, with attention paid to mental well-being as well as to somatic disease manifestations.

Keyphrases

patient reported
signaling pathway
mental health
lps induced
oxidative stress
psychometric properties
emergency department
primary care
pi k akt
nuclear factor
physical activity
sleep quality
depressive symptoms
working memory
immune response
gene expression
cell proliferation
toll like receptor