Childhood neurodivergent traits, inflammation and chronic disabling fatigue in adolescence: a longitudinal case-control study.

Lisa QuadtJenny CsecsRod BondNeil A HarrisonHugo D CritchleyKevin A DaviesJessica Anne Eccles

Published in: BMJ open (2024)

Our results indicate higher risk of chronic disabling fatigue for children with neurodivergent traits, likely linked to higher levels of inflammation. The implementation of transdiagnostic screening criteria to inform support strategies to counteract risk early in life is recommended.

Keyphrases

oxidative stress
genome wide
sleep quality
healthcare
primary care
young adults
depressive symptoms
quality improvement
dna methylation
gene expression
early life