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The inhibition of Src kinase suppresses the production of matrix metalloproteinases in from synovial fibroblasts and inhibits MAPK and STATs pathways

Demet Yalçın KehribarMetin ÖzgenServet YolbasAhmet YıldırımEbru Onalan EtemOsman Çiftçiİbrahim Hanifi ÖzercanSüleyman Serdar Koca
Published in: Turkish journal of medical sciences (2021)
The present study shows that the inhibition of Src kinase has antiarthritic potentials in both in vivo and in vitro settings. Src kinase inhibition may be candidate to further research in human RA.
Keyphrases
  • tyrosine kinase
  • protein kinase
  • signaling pathway
  • endothelial cells
  • oxidative stress
  • induced pluripotent stem cells