Data-Driven Patient Clustering and Differential Clinical Outcomes in the Brigham and Women's Rheumatoid Arthritis Sequential Study Registry.

Jeffrey R CurtisMichael WeinblattKenneth G SaagVivian P BykerkDaniel E FurstStefano FioreGregory St JohnToshio KimuraShen ZhengClifton O BinghamGrace WrightMartin J BergmanKamala NolaChristina Charles-SchoemanNancy A Shadick

Published in: Arthritis care & research (2021)

Data-driven analysis of the BRASS registry identified 5 distinct phenotypes of RA. These results illustrate the potential of data-driven patient profiling as a tool to support personalized medicine in RA. Validation in an independent data set is ongoing.

Keyphrases

rheumatoid arthritis
disease activity
case report
ankylosing spondylitis
single cell
interstitial lung disease
polycystic ovary syndrome
electronic health record
machine learning
type diabetes
adipose tissue
metabolic syndrome
systemic sclerosis
data analysis
cervical cancer screening