Natural combinatorial genetics and prolific polyamine production enable siderophore diversification in Serratia plymuthica.
Sara CletoKristina HaslingerKristala L J PratherTimothy K LuPublished in: BMC biology (2021)
This study shows the natural occurrence of serratiochelins, photobactin, enterobactin, and aerobactin in a single bacterial species and illuminates the interplay between siderophore biosynthetic pathways and polyamine production, indicating routes of molecular diversification. Given its natural yields of diaminopropane (97.75 μmol/g DW) and putrescine (30.83 μmol/g DW), S. plymuthica can be exploited for the industrial production of these compounds.