Maternal betaine supplementation ameliorates fatty liver disease in offspring mice by inhibiting hepatic NLRP3 inflammasome activation.

Lun Li Liuqiao Sun Xiaoping Liang Qian Ou Xuying Tan Fangyuan Li Zhiwei Lai Chenghe Ding Hangjun Chen Xinxue Yu Qiongmei Wu Jun Wei Feng Wu Li Jun Wang

Published in: Nutrition research and practice (2023)

The lipotropic and anti-inflammatory effect of maternal betaine supplementation may be associated with the inhibition of NLRP3 inflammasome in the livers of the offspring mice.

Keyphrases

nlrp inflammasome
high fat diet induced
high fat diet
anti inflammatory
birth weight
pregnancy outcomes
signaling pathway
insulin resistance
mouse model
type diabetes
metabolic syndrome
gestational age