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Heterozygous pathogenic variants involving CBFB cause a new skeletal disorder resembling cleidocranial dysplasia.

Tessi BeyltjensEveline BoudinNicole RevencuNele BoeckxMiriam BertrandLeon SchützTobias B HaackAxel WeberEleni BiliouriMateja VinkšelAnja ZagoženBorut PeterlinShashidhar PaiAida TelegrafiLindsay B HendersonCourtney EllsLesley TurnerWim WuytsWim Van HulGretl HendrickxGeert R Mortier
Published in: Journal of medical genetics (2022)
in a cohort of eight individuals with clinical and radiographic features reminiscent of CCD.
Keyphrases
  • early onset
  • copy number
  • gene expression
  • dna methylation