Association of Y chromosome AZF region microdeletions with recurrent miscarriage in Iranian couples: A case-control study.

Nasrin Pazoki Mitra Salehi Seyed Abdolhamid Angaji Meghdad Abdollahpour-Alitappeh

Published in: Molecular genetics & genomic medicine (2024)

Microdeletions in sY134 (AZFb) were significantly associated with RPL in Iranian men (p = 0.03). AZF microdeletion screening in couples with RPL can provide valuable information for ethnical genetic counseling and management of recurrent miscarriage. Further studies on larger populations or across various ethnic groups, conclusions and the inclusion of other factors like epigenetic changes explain the role of AZF microdeletions in RPL.

Keyphrases

copy number
dna methylation
intimate partner violence
gene expression
middle aged
smoking cessation
case control
hiv testing
men who have sex with men
hiv infected