Lewy Body Disease Primate Model with α-Synuclein Propagation from the Olfactory Bulb.
Masanori SawamuraHirotaka OnoeHideo TsukadaKaoru IsaHodaka YamakadoShinya OkudaMasashi IkunoYusuke HatanakaShigeo MurayamaNorihito UemuraTadashi IsaRyosuke TakahashiPublished in: Movement disorders : official journal of the Movement Disorder Society (2022)
We generated a novel nonhuman primate LBD model with α-Syn propagation from the OB. This model suggests that α-Syn propagation from the OB is related to OB atrophy and cerebral glucose hypometabolism in LBDs. © 2022 International Parkinson and Movement Disorder Society.