Early-Stage Breast Cancer Detection in Breast Milk.

Cristina Saura Carolina Ortiz Judit Matito Enrique J Arenas Lahuerta Anna Suñol Ágatha Martín Octavi Córdoba Alex Martínez-Sabadell Itziar Garcia-Ruiz Ignacio Miranda Clara Morales-Comas Estela Carrasco Cristina Viaplana Vicente Peg Paolo G Nuciforo Neus Bayó-Puxan Alberto Gonzalez-Medina Josep M Miquel Marina Gómez-Rey Guillermo Villacampa Silvia A Martínez Martín Espinosa-Bravo Judith Balmaña Rodrigo Dienstmann Joaquín Arribas Josep Tabernero Ana Vivancos Miriam Sansó

Published in: Cancer discovery (2023)

For the first time, we show that BM obtained from patients with breast cancer carries ctDNA, surpassing plasma-based liquid biopsy for detection and molecular profiling of early-stage breast cancer, even prior to diagnosis by image.

Keyphrases

early stage
loop mediated isothermal amplification
real time pcr
sentinel lymph node
label free
deep learning
single cell
machine learning
single molecule
lymph node