Esophageal hyperkeratosis as an uncommon manifestation of gastroesophageal reflux disease.

Laura Sánchez-Delgado Esteban Fuentes-ValenzuelaBeatriz Burgueño-GómezElda Paola Oyarzún BahamondeCarlos Maroto-MartínSamuel Fernández-PradaLaura Juan CasamayorMiryam Moreta Rodríguez

Published in: Revista espanola de enfermedades digestivas : organo oficial de la Sociedad Espanola de Patologia Digestiva (2022)

We present the case of a 66-year-old woman with intermittent dysphagia and esophageal food impaction. The endoscopic examination showed an upper and middle esophagus with a diffuse circumferential, white, crackleware epithelium. Esophageal biopsies revealed acanthosis and papillomatosis with diffuse hyperkeratosis. High dose of Proton pump inhibitors was initiated with improvement of all symptoms 6 weeks later.

Keyphrases

high dose
gastroesophageal reflux disease
ultrasound guided
low grade
low dose
high intensity
single cell
stem cell transplantation
human health
risk assessment
depressive symptoms
physical activity