Reprogramming a Doxycycline-Inducible Gene Switch System for Bacteria-Mediated Cancer Therapy.

Hien Thi-Thu NgoDinh-Huy NguyenSung-Hwan YouKhuynh Van NguyenSo-Young KimYeongjin HongJung-Joon Min

Published in: Molecular imaging and biology (2023)

These results suggest that attenuated S. typhimurium carrying this novel gene switch system elicited significant therapeutic effects through a single induction triggering and were a potential biotherapeutic agent for tumor therapy.

Keyphrases

cancer therapy
copy number
genome wide
genome wide identification
dna methylation
risk assessment
transcription factor
bone marrow