A case report of spastic diplegic cerebral palsy in a late preterm child with hypoplastic left heart syndrome.
Alexa C EscapitaJulienne G ThomasTara L JohnsonPublished in: Translational pediatrics (2024)
This is an interesting case report of spastic diplegic cerebral palsy in a late preterm infant with critical CHD. When making a diagnosis of cerebral palsy, it is important to consider the etiology of the motor impairment. Selective vulnerability may have played a factor in this child's condition. The most vulnerable part of the neonatal brain is the periventricular white matter; cerebral hypoxia can lead to periventricular leukomalacia. Children with CHD have brain dysmaturity beginning in-utero. Thus, it is possible that this child's brain dysmaturity may have increased his susceptibility to periventricular leukomalacia. Because most children with CHD have gross motor delays in infancy, it may be challenging to make a definitive diagnosis of cerebral palsy in an infant with critical CHD. Children with cerebral palsy have early motor delays that persist throughout life. It is the identification of persistent motor impairments through repeat evaluations that enabled this child's cerebral palsy diagnosis. This illustrates the importance of developmental surveillance in children with critical CHD.
Keyphrases
- cerebral palsy
- white matter
- mental health
- children with cerebral palsy
- case report
- young adults
- resting state
- multiple sclerosis
- cerebral ischemia
- low birth weight
- public health
- heart failure
- functional connectivity
- preterm birth
- climate change
- endothelial cells
- atrial fibrillation
- gestational age
- squamous cell carcinoma
- preterm infants
- blood brain barrier
- brain injury
- bioinformatics analysis
- rectal cancer