ANGPTL4 gene E40K variation protects against obesity-associated dyslipidemia in participants with obesity.

D BailettiL BertocciniR M MancinaI BarchettaD CapocciaE CossuA PujiaA LenziF LeonettiM G CavalloS RomeoMarco Giorgio Baroni

Published in: Obesity science & practice (2018)

In participants with obesity the ANGPTL4-E40K variant protects against dyslipidemia. The phenotype of obese E40K carriers is that of a patient with obesity without metabolic alterations, similar to the phenotype described as metabolic healthy obesity.

Keyphrases

weight loss
metabolic syndrome
insulin resistance
type diabetes
high fat diet induced
weight gain
bariatric surgery
adipose tissue
body mass index
gene expression
physical activity
obese patients