High Baseline Levels of Tumor Necrosis Factor Receptor 1 Are Associated With Progression of Kidney Disease in Indigenous Australians With Diabetes: The eGFR Follow-up Study.
Elizabeth Laurel Mary BarrFederica BarziJaquelyne T HughesGeorge JerumsWendy E HoyKerin O'DeaGraham R D JonesPaul D LawtonAlex D H BrownMark ThomasElif Ilhan EkinciAshim SinhaAlan CassRichard J MacIsaacLouise J Maple-BrownPublished in: Diabetes care (2018)
sTNFR1 is associated with greater kidney disease progression independent of albuminuria and eGFR in Indigenous Australians with diabetes. Further research is required to assess whether TNFR1 operates independently of other metabolic factors associated with kidney disease progression.