Evaluation and deployment of isotype-specific salivary antibody assays for detecting previous SARS-CoV-2 infection in children and adults.
Amy C ThomasElizabeth OliverHolly E BaumKapil GuptaKathryn L ShelleyAnna E LongHayley E JonesJoyce SmithBenjamin HitchingsNatalie di BartoloKate VasileiouFruzsina RabiHanin AlamirMalak EghleilibOre FrancisJennifer OliverBegonia Morales-AzaUlrike ObstDebbie ShattockRachael BarrLucy CollingwoodKaltun DualeNiall GraceGuillaume Gonnage LiveraLindsay BishopHarriet DowningFernanda RodriguesNicholas John TimpsonCaroline L ReltonAshley Mark ToyeDerek N WoolfsonImre BergerAnu GoenkaAndrew D DavidsonKathleen M GillespieAlistair J K WilliamsMick BaileyEllen Brooks-PollockAdam FinnAlice Hallidaynull nullPublished in: Communications medicine (2023)
Through robust standardisation, evaluation and field-testing, this work provides a platform for further studies investigating SARS-CoV-2 transmission and mucosal immunity with the potential for expanding salivo-surveillance to other respiratory infections in hard-to-reach settings.