Lingguizhugan Decoction Protects against High-Fat-Diet-Induced Nonalcoholic Fatty Liver Disease by Alleviating Oxidative Stress and Activating Cholesterol Secretion.

Lili Yang Weili LinColleen A NugentShijun Hao Haiyan Song Tao Liu Peiyong Zheng

Published in: International journal of genomics (2017)

Our study revealed a "two-hits-targeting" mechanism of LGZG in the treatment for NAFLD: alleviating oxidative stress and activating cholesterol secretion.

Keyphrases

oxidative stress
high fat diet induced
signaling pathway
insulin resistance
low density lipoprotein
dna damage
induced apoptosis
ischemia reperfusion injury
diabetic rats
adipose tissue
heat shock
replacement therapy
heat stress