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ALK inhibitors for non-small cell lung cancer: A systematic review and network meta-analysis.

Jesse ElliottZemin BaiShu-Ching HsiehShannon E KellyLi ChenBecky SkidmoreSaid YousefCarine ZhengDavid J StewartGeorge A Wells
Published in: PloS one (2020)
Treatment-related deaths were infrequent among ALK-positive NSCLC. PFS may be improved by alectinib and brigatinib relative to other ALK inhibitors; however, the assessment of OS is likely confounded by treatment crossover and should be interpreted with caution.
Keyphrases
  • advanced non small cell lung cancer
  • small cell lung cancer
  • epidermal growth factor receptor
  • open label
  • smoking cessation
  • study protocol