Chemogenetic suppression of anterior cingulate cortical neurons projecting to the visual cortex disrupts attentional behavior in mice.
Kevin J NormanHiroyuki KoikeSarah E McCraneyYury GarkunJulia BatehElisa N FalkSusanna ImKeaven CaroMichael P DemarsHirofumi MorishitaPublished in: Neuropsychopharmacology reports (2021)
These results identify long-range frontal-sensory ACAVIS projection neurons as a key enactor of top-down attentional behavior and may serve as a beneficial therapeutic target.