Intra-Articular Mineralization on Knee CT and Risk of Cartilage Damage: The Multicenter Osteoarthritis Study.
Jean W LiewMohammed JarrayaAli GuermaziDavid T FelsonMichael NevittCora E LewisJames TornerFrank W RoemerMichel D CremaNa WangGabriela V RabasaFabio BecceTristan PascartTuhina NeogiPublished in: Arthritis & rheumatology (Hoboken, N.J.) (2024)
CT-detected IA mineralization in the cartilage was associated with higher risk of MRI cartilage worsening in the same compartment and subregion over two years. These findings suggest potential localized, tissue-specific effects of IA mineralization on cartilage pathology in knee OA.
Keyphrases
- knee osteoarthritis
- contrast enhanced
- extracellular matrix
- total knee arthroplasty
- computed tomography
- magnetic resonance imaging
- image quality
- dual energy
- magnetic resonance
- positron emission tomography
- oxidative stress
- clinical trial
- risk assessment
- anterior cruciate ligament
- anterior cruciate ligament reconstruction
- climate change
- double blind