Nasopharyngeal Metastasis from Breast Carcinoma: A Case Report and a Review of the Literature.
Moncef SellamiSouha KallelMariam Ben AyedManel MellouliTahya Sellami BoudawaraMalek MnejjaBouthaina HammamiImen AchourIlhem CharfeddinePublished in: Ear, nose, & throat journal (2022)
Metastasis to the nasopharynx is a rare clinical entity. Breast carcinoma is one of the primary tumors that can be responsible for a nasopharyngeal metastasis, which is an extremely rare occurrence. We report the case of a 50-year-old woman with a history of a confirmed breast carcinoma under chemotherapy who presented to our department with a unilateral hearing loss and tinnitus. Nasal endoscopy revealed a small bulging mass at the posterior wall of the nasopharynx. The biopsy of the lesion showed an infiltration of the nasopharyngeal mucosa by a mammary adenocarcinoma that was positive for estrogen and progesterone receptors and negative for human epidermal growth factor receptor 2. Computed tomography scan revealed a thickening of the nasopharyngeal mucosa, a pleural and pericardial effusion and diffused secondary bone lesions. The patient received chemotherapy. Control revealed a partial regression of the nasopharyngeal mass. The patient is still under chemotherapy.
Keyphrases
- epidermal growth factor receptor
- computed tomography
- locally advanced
- hearing loss
- single cell
- case report
- endothelial cells
- advanced non small cell lung cancer
- squamous cell carcinoma
- magnetic resonance imaging
- rectal cancer
- risk assessment
- estrogen receptor
- bone mineral density
- body composition
- chemotherapy induced
- contrast enhanced
- tertiary care
- pet ct
- postmenopausal women
- bone loss