Performance of Ultrasound in the Diagnosis of Gout in a Multicenter Study: Comparison With Monosodium Urate Monohydrate Crystal Analysis as the Gold Standard.
Alexis OgdieWilliam John TaylorTuhina NeogiJaap FransenTim L JansenH Ralph SchumacherWorawit LouthrenooJanitzia Vazquez-MelladoMaxim EliseevGeraldine McCarthyLisa K StampFernando Perez-RuizFrancisca SiveraHang-Korng EaMartijn GerritsenGiovanni CagnottoLorenzo CavagnaChingtsai LinYin-Yi ChouAnne-Kathrin TauscheManuella Lima Gomes OchtropMatthijs JanssenJiunn-Horng ChenOle SlotJuris LazovskisDouglas WhiteMarco A CimminoTill UhligNicola DalbethPublished in: Arthritis & rheumatology (Hoboken, N.J.) (2017)
US features of MSU crystal deposition had high specificity and high PPV but more limited sensitivity for early gout. The specificity remained high in subjects with early disease and without clinical signs of tophi.