B cells response directed against Cut4 and CFP21 lipolytic enzymes in active and latent tuberculosis infections.

Wendy RénierArnaud BourdinPierre-Alain RubboMarianne PeriesLuc DedieuSophie BendrissLaurent KremerStéphane CanaanDominique TerruSylvain GodreuilNicolas NagotPhilippe Van de PerreEdouard Tuaillon

Published in: PloS one (2018)

Circulating IgG SCs directed against Cut4 or CFP21 were mostly detected in patients presenting an active form of the disease, suggesting that TB reactivation triggers an immune response against these two antigens.

Keyphrases

immune response
end stage renal disease
mycobacterium tuberculosis
newly diagnosed

chronic kidney disease
ejection fraction
dendritic cells
peritoneal dialysis

emergency department
toll like receptor
patient reported outcomes

hepatitis c virus
patient reported
antiretroviral therapy