Login / Signup

Vaccination against SARS-CoV-2 and disease enhancement - knowns and unknowns.

Raphaël M ZellwegerT Anh WartelFlorian MarksManki SongJerome H Kim
Published in: Expert review of vaccines (2020)
We compile and propose avenues to investigate the risk of vaccine-mediated disease enhancement both during pre-clinical and early clinical development. While the pressing need for a vaccine against COVID-19 (and future epidemic coronaviruses) cannot be ignored, we advocate to keep safety at the center of the debate. Protecting individuals with effective and safe vaccines should be a priority, even during extraordinary times like the COVID-19 pandemic.
Keyphrases
  • sars cov
  • respiratory syndrome coronavirus
  • coronavirus disease