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Label-Free Characterization of Atherosclerotic Plaques Via High-Resolution Multispectral Fluorescence Lifetime Imaging Microscopy.

Jeongmoo HanSunwon KimHyun Jung KimHyeong Soo NamMin Woo LeeJoon Woo SongJin Won KimHongki Yoo
Published in: Arteriosclerosis, thrombosis, and vascular biology (2023)
FLIM provided detailed pixel-level AFL investigation of the complex composition of coronary artery and atheroma. Our FLIM strategy enabling an automated, comprehensive visualization of multiple plaque components from unlabeled sections will be highly useful to efficiently evaluate ex vivo samples without the need for histological staining and analysis.
Keyphrases
  • high resolution
  • label free
  • coronary artery
  • single molecule
  • pulmonary artery
  • fluorescence imaging
  • high speed
  • coronary artery disease
  • flow cytometry
  • pulmonary hypertension
  • optical coherence tomography