Antidepressant use in relation to dementia risk, cognitive decline, and brain atrophy.
Ilse Vom HofeBruno H StrickerMeike W VernooijM Kamran IkramM Arfan IkramSirwan K L DarweeshPublished in: Alzheimer's & dementia : the journal of the Alzheimer's Association (2024)
Antidepressant medications are frequently prescribed, especially among older adults. In this study, antidepressant use was not associated with long-term dementia risk. Antidepressant use was not associated with cognitive decline or brain atrophy. Our results support safe prescription in an older, cognitively healthy population.