Comparing Circulating Tumor Cell Counts with Dynamic Tumor Size Changes as Predictor of Overall Survival: A Quantitative Modeling Framework.
Ida NetterbergMats O KarlssonLeon W M M TerstappenMiriam KoopmanCornelis J A PuntLena E FribergPublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2020)
Time-varying CTC counts can be useful for early predicting OS in patients with mCRC, and may therefore have potential for model-based treatment individualization. Although tumor size was connected to CTC, its link to OS was weaker.