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Associations of ARMS2 and CFH Gene Polymorphisms with Neovascular Age-Related Macular Degeneration.

Supanji SupanjiDewi Fathin RomdhoniyyahMuhammad Bayu SasongkoAngela Nurini AgniFirman Setya WardhanaTri Wahyu WidayantiMuhammad Eko PrayogoAyudha Bahana Ilham PerdamaianAninditta DianratriMasashi KawaichiChio Oka
Published in: Clinical ophthalmology (Auckland, N.Z.) (2021)
Our findings indicate that ARMS2 A69S and ARMS2 del443ins54 polymorphisms are strongly associated with the risk of nAMD for the first time in an Indonesian population. The risk of nAMD increased when the presence of risk alleles from ARMS2 A69S was combined with the presence of hypertension.
Keyphrases
  • age related macular degeneration
  • blood pressure
  • endothelial cells