Is it time to reconsider the administration of thiamine alone or in combination with vitamin C in critically ill patients? A meta-analysis of clinical trial studies.
Nafiseh Shokri-MashhadiAli AliyariZahra HajhashemySaeed SaadatMohammad Hossein RouhaniPublished in: Journal of intensive care (2022)
In contrast to HVT, thiamine supplementation alone was associated with increased mortality rate in ICU. However, co-supplementation of thiamine and vitamin C had a significant decreasing effect on SOFA score.