Trajectories of Uremic Symptom Severity and Kidney Function in Patients with Chronic Kidney Disease.
Kendra E WulczynSophia H ZhaoEugene P RheeSahir KalimTariq ShafiPublished in: Clinical journal of the American Society of Nephrology : CJASN (2022)
The prevalence of uremic symptoms in CKD is high, with significant variability in patient symptom change over time. Declines in eGFR were associated with worsening of uremic symptom severity, but the magnitude of these changes is small and of uncertain clinical significance.