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Brain Targeting of Citicoline Sodium via Hyaluronic Acid-Decorated Novel Nano-Transbilosomes for Mitigation of Alzheimer's Disease in a Rat Model: Formulation, Optimization, in vitro and in vivo Assessment.

Kariman M AbouElhassanHatem A SarhanAmal K HusseinAshraf TayeYasmin M AhmedMohamed A Safwat
Published in: International journal of nanomedicine (2022)
Succinctly, the innovative loading of CIT-HA*TBLs thermogel is a prospectively invaluable intranasal drug delivery system that can raise the efficacy of CIT in Alzheimer's management.
Keyphrases
  • hyaluronic acid
  • cognitive decline
  • climate change
  • resting state
  • drug delivery
  • white matter
  • cancer therapy
  • reduced graphene oxide
  • mild cognitive impairment
  • quantum dots
  • functional connectivity
  • gold nanoparticles