The induced decrease in TLR2 and TLR4 by cerebrolysin in the alcoholic liver of rats.

Javad MahmoudiAta MahmoodpoorMehdi AmirniaTohid KazemiPooneh Chokhachi BaradaranShirin Sheikh NajafiSaeed Sadigh-EteghadFereshteh FarajdokhtHuaxi XuMobina BelalzadehSiamak Sandoghchian Shotorbani

Published in: Journal of cellular physiology (2019)

The present study demonstrated that the anti-inflammatory effect of cerebrolysin can decrease the TLR2 and TLR4 expressions through downregulating nuclear factor-κB pathway in the ALD disease.

Keyphrases

toll like receptor
nuclear factor
inflammatory response
immune response
anti inflammatory
high glucose
endothelial cells
oxidative stress